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產(chǎn)品規(guī)格
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BN41738R-50ul
50ul
￥1486.00
交叉反應(yīng)：Human,Rat(predicted:Mouse,Dog,Pig,Cow,Rabbit,Sheep,Goat) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
BN41738R-100ul
100ul
￥2360.00
交叉反應(yīng)：Human,Rat(predicted:Mouse,Dog,Pig,Cow,Rabbit,Sheep,Goat) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
BN41738R-200ul
200ul
￥3490.00
交叉反應(yīng)：Human,Rat(predicted:Mouse,Dog,Pig,Cow,Rabbit,Sheep,Goat) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
產(chǎn)品描述
| 英文名稱 | CEBP-alpha |
| 中文名稱 | 轉(zhuǎn)錄調(diào)節(jié)因子C/EBP α 抗體 |
| 別 名 | Apoptotic cysteine protease; Apoptotic protease Mch 5; C/EBP alpha; CAP4; Caspase 8 precursor; CCAAT Enhancer Binding Protein alpha; CEBP; CEBP A; CEBP alpha; CEBPA; FADD homologous ICE/CED 3 like protease; FADD like ICE; FLICE; ICE like apoptotic protease 5; ICE8; MACH; MCH5; MORT1 associated CED 3 homolog; |
| 研究領(lǐng)域 | 腫瘤 心血管 染色質(zhì)和核信號 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Rat, (predicted: Mouse, Dog, Pig, Cow, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 39kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CEBP-alpha:251-358/358 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells. [provided by RefSeq, Jul 2008]. Function: C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Subunit: Interacts with PRDM16. Binds DNA as a dimer and can form stable heterodimers with C/EBP beta and gamma. Interacts with UBN1. Interacts with HBV protein X. Interacts with ZNF638; this interaction increases transcriptional activation. Subcellular Location: Nucleus. Similarity: Belongs to the bZIP family. C/EBP subfamily. Contains 1 bZIP domain. SWISS: P49715 Gene ID: 1050 Database links: Entrez Gene: 1050 Human Entrez Gene: 12606 Mouse Omim: 116897 Human SwissProt: P49715 Human SwissProt: P53566 Mouse Unigene: 76171 Human Unigene: 349667 Mouse Unigene: 153603 Rat Unigene: 204833 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
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